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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

最佳迷你剧/电影:《美国罪案故事:公诉辛普森》(“The People v. O. J. Simpson: American Crime Story”, FX)
自从2008年智能手机应用商店开始运营以来,达洛伊西奥就着手设计iPhone手机应用软件。那时12岁的他住在伦敦的温布尔顿,用卧室里的Mac电脑来工作。因为年纪太小,他在填写苹果(Apple)开发执照申请时用的都是他爸爸的名字。这之前他没在学校受过正式的电脑培训,他的父母(一个是律师,一个是商界管理人士)也都不从事技术行业工作。他几乎是完全靠刷网页、看教程来自学编程的。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

“These kinds of questions are really front and center, even though they’re not necessarily verbalized.”
Astronomers confirmed a key part of Einstein’s general theory of relativity in 2016 when they announced that the LIGO array had detected gravitational waves released by the collision of two black holes. The researchers won a Nobel Prize for the discovery. But they’re not done: In October, scientists announced the finding of two dead stars colliding — not only hearing the ripples in space-time they made, but confirming the event visually with powerful telescopes. Collisions of neutron stars are believed to be the source of all heavy metals in the universe, including gold and silver, and the detection by LIGO helps verify accepted explanations of how the chemistry of the universe formed.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

9.The Company Isn't Doing Well

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

排名前20的大学有13所大学是美国的大学、还有4所英国大学和3所其他大学。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

It seems safe to predict lots more noise and very little progress for the rest of 2017. And that will continue to be a damaging combination for business and the UK economy.
节目6 小品《想跳就跳》,潘长江 蔡明 郭丰周
每季度,英特尔(Intel)都会铺上红地毯,欢迎加入公司的新员工。在入职培训的第一天,每位新人都会受到摄影师和摄像师的夹道欢迎,上台做完自我介绍,新人们就能领取一份欢迎大礼包(还有周围新同事们的热烈掌声)。
Hunger Games star Jennifer Lawrence on Tuesday topped a Forbes magazine list of the world’s highest-paid actress for the second straight year, earning some $46 million, followed by Melissa McCarthy.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
From the themed collection: 加速形成京津冀“1小时通勤圈”
Perspective

Trends and targets in antiviral phototherapy

Summly的两位员工将迁至雅虎的加利福尼亚州总部,但就目前而言,达洛伊西奥抵挡住了硅谷的诱惑。
Mr Talbot notes that regulators in Japan are encouraging fee-based sales with a new fiduciary code and other measures that will play to the low-cost appeal of ETFs.
['hedwei]
Mr Trump is almost a textbook demagogue.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

4. Rihanna

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

All three of the big worldwide financial bubbles that have blow up in the last three decades have 'been fueled by the Fed keeping policy rates below the nominal growth rate of the economy far too long, ' says global strategist Kit Juckes of the French bank Societe Generale.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

2017年度国家公务员考试上周日开考,大学生自主创业和"玉兔"月球车等最近的热门话题进入国考考题。
然而,007系列电影主题曲却并没有人们想象的那么历史悠久。第一部《诺博士》和第二部《俄罗斯之恋》没有开场曲,而是安排了管弦乐。《诺博士》甚至插入了《三只瞎老鼠》的怪异演奏。随后,《女王密使》才开始有了开场曲,并且在影片的中间和结尾插入了主题曲。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 销售率不足4成 限房价项目压力大
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

A New Year greeting to cheer you from your daughters.
“Why do we keep getting so many record-warm years?” Dr. Schmidt asked in an interview. “It’s because the planet is warming. The basic issue is the long-term trend, and it is not going away.”

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Economists had likewise expected year-to-date urban fixed asset investment, a rough proxy for long-term spending, to remain at September’s level of 8.2 per cent year on year growth.
动作、探险剧《盗墓笔记》改编自徐磊(笔名南派三叔)的畅销网络小说。它也是中国第一部季播网络剧,预计该小说将被改编为8季,每年播出一季。第一季于2015年6月播出。同名系列小说讲诉了吴邪和小伙伴们在古墓探险的故事,该小说2006年在网上发布后受到了大量粉丝的追捧。因此,大家对改编电视剧期望颇高,不过它却让粉丝们大跌眼镜。尽管首播2分钟后,网络点击量就超过了2千4百万,不过第一季的薄弱情节和粗劣品质很快就被粉丝们炮轰了。剧中的一些台词甚至成了社交媒体上调侃的段子。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

指数: 97.8
Rounding out the top three is Fleetwood Mac at $59.5 million. Though the band contains three men, it also boasts two high-profile ladies—Stevie Nicks and the recently-returned Christine McVie—rendering the group eligible for this list. Its On With The Show tour included 86 concerts during our scoring period, grossing well over $1 million per city.
The three bubbles: The Asian Bubble in the early '90s, Dot-com Bubble of the late '90s and what Juckes calls the Great Big Credit Bubble that triggered the 2008 Wall Street meltdown.
"Sure, there are only whites in the stadium. It comes down to money," said Ana Beatriz Ferreira, a 27-year-old parking attendant in Rio de Janeiro, who is black. "Nobody I know could find affordable tickets."

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Two United States cities have seen significant increases in costs, with Los Angeles rising 19 places to enter the top 10.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Some hits have gone so far over the top they should be winded, yet instead keep on puffing gusts of hot air, including “Downton Abbey,” “Scandal” and “Revenge.” A new addition on ABC, “How to Get Away With Murder” was a fun substitute, a lurid nighttime soap opera about lawbreaking defense lawyers — “Law & Disorder.”
7.别问警察怎样去伦敦西区最快,也别问他如何使用牡蛎交通卡。他也很想帮你,不过他是从西米德兰兹郡来的。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

第一架无线电操纵的无人驾驶飞机可追溯到1916年。英国发明家阿奇博尔德·洛设计并试飞了第一架无人遥控飞机。它是为了反攻德国齐柏林飞艇而制作的,在第一次世界大战中参与了对地面攻击的战斗。无人机由木和锡制成,它的机翼用的是其他双翼飞机的较低机翼。总的来说,无人机是有些失败的,因为它的引擎噪音干扰了无线操作。1916年,索普威斯飞松公司也尝试制作无人机,他们将无线电设备放置在无人机的尾部,这样引擎就不会干扰到它的信号。但因一次地面上的意外事故,他们的无人机再未起飞:当洛操作无人机飞到高级军官面前时,他原本计划会在1917年再次试飞无人机。但无人机从卡车的后面发射后,飞了一段时间便因引擎故障而坠毁,差点要了在场的军官的命。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

2013 Rank: 14

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

你如何知道你需要喝水了?这有一系列的诱因:嘴唇发干、头晕、头痛、尿量低和口渴。然而,这种智能瓶能在你的身体意识到缺水前就提醒你。
strictly
因此,39%的90后试图避免使用手机所带来的负面影响,措施包括关闭APP的消息提示功能、限制社交媒体互动频率、以及在某些情况下完全不使用社交媒体等等。
Strengthening the all-around improvement of government

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

房地产经纪公司莱坊(Knight Frank)的数据显示,今年第一季度,香港豪宅租金同比下跌5.2%,跌幅超过内罗毕以外的任何其他城市。就在去年9月价格下跌之后,运动品牌阿迪达斯(Adidas)在香港租入了一间1.3万平方英尺的店铺,租金相比上一个租户、配饰品牌蔻驰(Coach)低了22%。
n. 预定,保留意见
Making Airbnb go away might not be so easy. A recent Quinnipiac poll found that 56 percent of the responders thought New Yorkers should be allowed to rent rooms out to strangers. “We don’t want to turn into hotels, but at the same time people want to rent out their apartments sometimes,” said Paul R. Gottsegen, the president of Halstead Management Company, which manages 250 residential properties in the city.
男女学员的薪资差距已扩大到17%,女性平均薪资为17万美元,男性则达到近20万美元。
本文为与《时代》杂志的合作内容。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

The nearest star, Proxima Centauri, has a planet orbiting it not much bigger than Earth. Its "year" is only 11 days. But it's in the habitable zone because Proxima Centauri is a red dwarf star about 100 times fainter than the sun. And there's hot news that a similar star, 40 light years away, may have three planets in its habitable zone.
The 25 most common passwords have been released by Splashdata which makes password management applications.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

泰国董里岛——董里岛是泰国东南部一个可被雷达侦测到的沉睡之省,游人可以在那里租长尾船,到岛屿之间穿行,还可以去看濒临灭绝的儒艮。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

n. 冰箱

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

2013年排名:2
2016年的欧洲杯足球赛,俄罗斯与英国球迷因其粗鲁及流氓行为一直占据新闻头条。
The appointment of Inga Beale to run Lloyds of London and of Mary Barra to run General Motors marked an encouraging end to 2013. Progress for women in the coming year will continue to be too little and too slow, but you should expect to see women in positions of power and influence everywhere. Even Japan is starting to try to get women into work.
The seven large brick tombs were likelyconstructed for people of wealth, the researchers said.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Referencing the American chat show host, he quipped: 'I've always wanted to meet Jay Leno,' before laughing to himself. Clearly unimpressed, Dallas Buyers Club star Jared hit back: 'Sorry, what was your name again?'But audiences seemed to pick up on the atmosphere between the two, with one viewer joking: 'Think Jared Leto got a bit paranoid about Grinder looking at him.'
反对:在某种程度上,《三块广告牌》分裂了美国观众,它赢得最佳影片的希望或许会因此破灭。
Up to 10,000 copies of the film - a comedy about a fictional CIA plot to assassinate North Korean leader Kim Jong-Un - and 500,000 political leaflets are scheduled for a balloon-launch around 26 March.
单词fare 联想记忆:

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
From the themed collection: 防止用于减税资金变成“唐僧肉”
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

据透露,二月份哈迪德眯着眼睛试图模仿佛像,冒犯了许多人,在那之后她的签证申请就被驳回了。
(实际上,在过去三年的节日假期里,捷蓝航空公司绝对不是航班起飞延误最糟糕的航空公司。这项殊荣要授予Comair公司,这是达美航空公司经营地区航线的公司。不过该公司在2012年假日季节开始前停业,因此我们没有让这家公司上榜。)

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: “两材”旗下9家上市公司昨临停
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

10. 《66》(Sixty Six)。刘易斯·卡尔(Lewis Klahr)把数码短片精彩地汇集在一起,以一种英雄气概的方式复制流行文化,它只在MoMA上映过一晚。但他的作品也在洛杉矶和旧金山等城市上映,所以如果你住在附近,可以去看他的下一次展映。
美国上市交易相比2016年(多年来最疲弱的年份之一)出现起色。根据Dealogic的统计,今年迄今已有112笔IPO得到定价,而去年这个时候只有63笔。发行金额翻了一番多,达到316亿美元。
This journey into the mind and feelings of an 11-year-old-girl may be Pixar’s wildest adventure yet. It’s a very funny workplace sitcom (with exuberant, touching performances from Amy Poehler, Phyllis Smith, Mindy Kaling and others), an ingenious allegory of psychological development, and an almost unbearably moving and honest defense of the role of sadness in our lives. (Read the review.)
THE EFFECT OF RAPID CHANGE
The value of goods that crossed international borders last year fell 13.8 per cent in dollar terms — the first contraction since 2009 — according to the Netherlands Bureau of Economic Policy Analysis’s World Trade Monitor. Much of the slump was due to a slowdown in China and other emerging economies.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Pork and vegetable prices both dropped by more than 8 percent year-on-year.
Swyft now makes half of its money from ad campaigns like the one for Gwen Stefani. Swyft’s revenue has increased between 50% and 100% each month, Wray says. The other half comes from selling stickers—typically licensed from sports teams and entertainment brands like Shrek.
如果你有幸拥有一份工作,那么想要辞掉这份工作的想法听起来是荒唐的。在失业率大多数有史以来的最高的今天,大多数人正在因为被聘用而感谢他们的幸运星。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

《风骚律师》(Better Call Saul),AMC,2月8日播出。这是文斯·吉里根(Vice Gilligan)与彼得·古尔德(Peter Gould)的《绝命毒师》的衍生剧,或许是今年冬天最受期待的新剧了。鲍勃·奥登科克(Bob Odenkirk)饰演狡猾的律师索尔·古德曼(Saul Goodman),剧情设定在《绝命毒师》的故事发生之前,所以布莱恩·克莱斯顿(Bryan Cranston)或亚伦·保罗(Aaron Paul)至多只是客串出演而已。但观众们最喜欢的乔纳森·班克斯(Jonathan Banks)将在里面重现他在《绝命毒师》中的角色——冷静的行动执行者迈克·厄尔曼特劳特(Mike Ehrmantraut)。
李亦表示:“贫困阻碍了网民数量的进一步增加,使得网民数量占全部人口的比例只在50%左右。”

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: “一房二卖”引发了5起连环官司
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
From the themed collection: 家居行业瞄准电商蛋糕
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

哦,对了,我刚刚说了勒布朗·詹姆斯这个夏天其实是自由球员吗?
中国民航局局长冯正霖表示,因天气造成航班延误的比例由2015年的29.5%增至2016年的56.8%。
3、美酒佳人。 邦德走到哪里喝到哪里,美酒的确能帮他俘获佳人。喜欢喝一杯的人最容易在第一次约会时就抱得美人归。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

['θ?:tful]
A research team at the University of Chicago has solved this problem, producing hands that send electric signals to the brain. They've begun with monkeys as test subjects, studying the animals to see how their brains respond to touch. When outfitted with prosthetic hands that stimulate their brains that way, the monkeys respond just as though they physically touch objects themselves.
['pl?nit]

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 专家聚焦完善住房保障体系
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

报告指出,缺少资金和经验是大学生创业者们面临的最大障碍,40%的年轻创业者们依赖于诸如来自银行、投资机构、学校和政府等机构贷款的外部资金。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

周五,现代和爱茉莉太平洋的股价出现下跌,在首尔下午晚些时候的交易中分别下跌4.4%和12.5%。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
From the themed collection: 不动产登记跑出“孝感速度”
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

这也是精算师高居美国最佳工作榜首的原因之一。这是求职网站CareerCast.com最新调查结果,调查报告于周二发布。生物医学工程师排名第二位,2012年高居榜首的软件工程师如今排名第三。排名垫底的工作包括现役军人、伐木工人和报社记者。
包括圣诞购物季在内,第四季度的电脑出货量共计7190万台。IDC方面表示,这是自IDC公司开始追踪该数据以来最大的降幅。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

单词pandemic 联想记忆:
badminton;basketball;fencing;Judo;Ping Pang;taekwondo;Tennis;weightlifting;Wrestling;Volleyball;Boxing;Hocky.
“所以问题在于你如何将不可能化为可能?如何保证既忠于原始人物和设定,同时不冒犯21世纪的读者?
Whether or not any sort of BlackBerry-Samsung deal actually happens, the development highlights next wave of innovation (and litigation) in mobile technology: one centered on access control methods and containing corporate breachesin an increasingly mobile world.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

University officials said the letter was now on its way to him along with a T-shirt from the university.
Nearly all the entrepreneurs (93 per cent) rated their new skills as important or very important in their decision. “I understand the value of my skills without the ‘fear’ of not being employed,” said one.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

报告还发现,在“智力资本和创新”及“技术成熟度”等指标方面排名较高的城市综合排名也很高,这很明确地表明,技术上先进的城市更有可能成为“机遇城市”。
原指拍film用的film(n 胶卷)-轻而薄且不牢固的

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

“我们非常确信成交价会达到预测的最高价。”

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Talking about wanting to kill your boss may not be that uncommon, but it does put a damper on things when said boss actually ends up murdered. When the police came to ask questions, they ended up learning that the Cranston brothers had recently resigned to ride their motorcycles cross-country. Until they could be cleared, the two men were both suspects.
Autonomous cars: Researchers are working on devices that will automatically park your car in a parking lot without you being in, or near, the car. It will also slip a note under the wipers of the car next to it with your phone number and insurance carrier in case of any scratches.
一位伦敦软件神童的“硅谷梦”成真,雅虎(Yahoo)斥资近3000万美元收购了他制作的新闻应用。
Set in 1950's London, Reynolds Woodcock is a renowned dressmaker whose fastidious life is disrupted by a young, strong-willed woman, Alma, who becomes his muse and lover.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

在苹果(Apple)的蒂姆库克(Tim Cook)支持AR后,该技术可能是更大的机遇。苹果最新操作系统及新款手机iPhone X纳入了AR技术。
教育部还表示,公费留学学生的归国率达到了98%。公费留学生一般选择中国急需的专业,包括工程学、纯科学、农业和医学科学等。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
From the themed collection: 陶瓷大师王锡良名誉维权索赔1元
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Rounding out the top three is Chrissy Teigen, 31, who joins the list for the first time after raking in $13.5 million over the past 12 month-period.
v. 构成,把 ...
7. Smart cookie oven

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

If there are nine or 10 best picture nominees, it could grab a spot. Jordan Peele's screenplay looks certain to be recognized.
脱口秀主持兼喜剧演员艾伦·狄珍妮丝将会第二次主持奥斯卡颁奖典礼。
余秀华

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

8.你把简历留在了该死的打印机里!
INDOORS: This house was completed around 1848 and last updated in 2008. The front door has a transom and sidelights of red glass etched with a leaf motif. The first floor has a large living room with crown molding and two fireplaces, one of which warms the formal dining area. Off the living room is a family room with raised wall paneling, a wet bar and another dining area. French doors open to a slate patio. Several rooms have views of Little Narragansett Bay.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

The price of gold has risen 15 per cent since the beginning of 2017 to trade at $1,334.78 a troy ounce.
jewelry
不过,在这一反弹中也出现了奖金数额的下滑:去年的平均年终奖是12821元人民币(合1861美元),比2015年多了大约2000元人民币,却仍比2014年的平均值少了800元人民币。在奖金缩水的被调查者中,逾四分之一的人将原因归结为公司业绩太差。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

None of these conditions is in place now. Fed tightening, begun in December, has been put on hold. The federal funds rate (the interbank overnight lending rate) is estimated to be more than a percentage point below its natural level. And there have been no surprises from the Fed. Last December’s 25 basis point rise in the Fed’s policy rate, for example, was comprehensively signalled in advance.
“It’s eerie how similar this space is to CRM when Marc Benioff launched Salesforce.com,” said Mitch Harper, who co-founded the company in 2009 with co-CEO Eddie Machaalani. “The parallels are uncanny.”

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
From the themed collection: 海福乐五金携手AIM打造异动空间
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

对家长而言,整天抱着孩子非常费劲,尤其是孩子越来越大、越来越重的时候。
Ms Lewis urged people to contact family, neighbours or an animal shelter if they were no longer able to care for their pets.
amendment

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

节目16 武术《少年中国》,赵文卓 范龙飞 侯英岗

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
From the themed collection: 中国矿主的突围之路
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

不断上演的进球大战正是本届世界杯精彩绝伦之处。
大小:6364平方英尺(约591平方米)

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

The promotion of urbanization in central and western China has also attracted many members of the labor force from coastal cities in East China to inland regions, where the cost of living is much lower, Peng explained.
今年初,麦基在接受媒体采访时说:“虽然似乎有悖于直觉,但尽可能提高长期利润的最佳途径就是不要把利润作为公司的首要目标。”

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

采光。在工作中,光线是很重要的,不要用上大学时候的那个小台灯了,用个更别致更有创意的灯吧。
今年夏季,美国ETF管理的资产规模跨过3万亿美元大关,亚太ETF行业管理的资产仅成功爬上3500亿美元关口。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

She pointed to equal pay, saying it's not "just a woman's issue" but something that affects everyone. "If you have a wife, a mother, a sister, a daughter who is working and they are not being treated fairly, the whole family suffers," Clinton said.
6、沉溺于社交媒体

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

In early December, authorities announced that market circuit breakers would be introduced become effective from January 1 in an effort to limit the volatility seen during the savage, summer sell-off from June. The circuit breakers would see trading in shares, options and futures halted for 15 minutes if they fell by more than 5 per cent. On their first day of use, that first threshold was breached just after the return from the lunchbreak, prompting a 15-minute halt.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

整个夏天,每隔一周,Good Humor冰淇淋卡车在周五午餐时就会拜访这家公司。而在秋季,公司每个月有两个上午会给大家提供苹果酒和甜甜圈。
Baoneng’s raid has been bitterly resisted by Wang Shi, Vanke’s founder who has sought out white knights in a so far successful effort to retain control of the management-led company. The takeover battle fuelled a surge both in the price of Vanke’s Shenzhen-traded shares and Mr Yao’s known worth.
就零工经济的命运来说,英国将是一个值得关注的关键国家。英国政府将对一份关于英国法律是否跟得上这一新趋势的独立评估做出回应。考虑到政府的脆弱性和耗时的英国退欧进程,现在似乎不太可能出台大胆的政策行动——无论是支持还是反对在线劳动力平台。
例如,佳士得给威尼斯艺术家弗朗西斯科·丰泰巴索(Francesco Fontebasso)在18世纪中叶创作的油画《井边的丽贝卡和埃利泽》(Rebecca and Eliezer at the Well)的最低估价为12万英镑。根据Artnet的数据,在1990年的拍卖会上,这幅令人愉快的洛可可装饰风格的油画是以28.6万英镑购得的。在12月8日的拍卖会上,它仅得到一个电话出价——11.5万英镑(不含佣金),约合17万美元。而投资者们可不认为在购买沃霍尔(Warhol)或巴斯奎特(Basquiat)的作品25年之后会损失约40%。如果一幅早期绘画大师的作品被搁置在交易商的画廊里,想转卖它就更加困难。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

After a year of sexual harassment scandals that started in Silicon Valley and spread to just about every industry, women will try to capitalise on the momentum to push for permanent changes. And attention will focus on the plight of marginalised minorities, with so few black and Latino employees in the tech industry.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

n. (准备好演出的)节目,保留剧目,(计算机的)指令表
时间:2011-12-06 编辑:Jasmine
And, men are 2.8 times more likely to use this obvious phrase than women.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

报告还发现,在“智力资本和创新”及“技术成熟度”等指标方面排名较高的城市综合排名也很高,这很明确地表明,技术上先进的城市更有可能成为“机遇城市”。
[swift]

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

会。梅亚德是执政党革命制度党(PRI)的候选人。他主要的竞争对手是强硬的左翼领导人安德烈斯曼努埃尔洛佩斯奥夫拉多尔(Andrés Manuel López Obrador)——可以感召人群的激情演说家。梅亚德需要克服很多问题:在去年1月一夜间把油价上调20%、引发通胀飙升后,他必须说服选民自己仍然是可以信任的。他还必须证明自己是个有主见的人,而不仅仅是这届不受欢迎的政府的傀儡——在遏制猖獗的腐败和犯罪行为方面,这届政府极为失败。但是凭借强大的PRI拉票机器,他可能势不可挡。在墨西哥只有一轮选举的体制下,30%的选票可能就足以让他当选总统了。
4. Con Dao Isalsnd, Vietnam-Once the site of the infamous Con Dao prison, Vietnam's isolated archipelago of 16 islands known as the Con Dao Islands is starting to become known for its scenery and fresh seafood.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 2017,木门行业现状解析
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Author Anthony Horowitz has revealed the new book Trigger Mortis has been amended for modern readers and contains anti-smoking messages and for the first time an ‘outspoken’ gay friend.

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: 2013中国涂料品牌榜结果揭晓
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

draft
这种旅行枕可以随意弯曲变形,您的头怎么放都行。
桑尼伯恩和他的父母以及11岁的妹妹朱莉娅住在佛蒙特州的布里斯托尔,他正在寻求民主党的提名。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

To put this all in a bit more perspective, the current World Cup is averaging more goals than any of the top leagues around the world averaged in 2013/14. TheNetherlands' Eredivisie was the highest scoring of the top European leagues at 3.20 and the Bundesliga was just a shade behind at 3.16. No other top European league averaged more than 2.80 last season. In theAmericas, Major League Soccer is the current pace setter at 2.89 goals per game.
2017年,我国购买了14.1万台工业机器人,同比增长58.1%,然而在购买的机器人中,外资品牌占比近3/4,这表明国产与国外机器人制造商存在的差距仍在扩大。
The country's improved performance has notched the 17th place in "innovation quality", an indicator that looks at the caliber of universities, number of scientific publications and international patent filings.
定义自己

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 广州二手楼成交明显回升
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

有了这个支架,吊床随处都能搭。可以搭在水上、雪上、公路上。
The 8,000 volunteers who will welcome international visitors to London 2012 have been issued with a 66-page instruction manual, covering everything from foreign etiquette to uniform care and advice on dealing with journalists. But what of the visitors themselves? Could they not do with a manual outlining the customs, manners and practicalities of the islands they are visiting? We hereby present a simple guide to UK etiquette for the 2012 Olympics.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

与此同时,大学毕业生选择继续深造的意向也降低了,这让今年选择就业的人数比例达到了75.6%,而去年这一数据为71.2%。
1. Bottoms Up Beer System
这家总部位于伊利诺伊州皮奥利亚的重型机械制造商于1月份批准了100亿美元的股票回购,预计将在今年一季度回购17亿股股票,以完成先前75亿美元的回购计划。公司CEO道格o奥伯赫尔曼表示,正在进行的回购是“我们的现金流创纪录的结果”。(财富中文网)

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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France continues to hold the position as Germany's second largest trading partner in 2016, according to data from DIHK.
The 8 per cent year-on-year drop in profits last month compares with 4.2 per cent in November and is the biggest since the current data series began in late 2011, figures released on Tuesday showed.

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